Augmentin injection 600mg - Legal Category
mg/mg Tablets: Each white oval film-coated tablet, debossed with AUGMENTIN on one side and / on the other side, contains mg amoxicillin as the trihydrate and mg clavulanic acid as the potassium salt.
The dose of Augmentin that is selected to treat an individual infection should 600mg into account: The use of alternative presentations of Augmentin e. This Augmentin powder for solution for injection or infusion provides a total daily dose of mg amoxicillin and mg clavulanic acid injection administered as recommended augmentin.
If it is considered that a higher daily dose of amoxicillin is required it is recommended that an alternative intravenous formulation of Augmentin is selected in order to avoid injection of unnecessarily high daily doses of clavulanic acid. The duration of therapy should be determined by augmentin response of the patient. Treatment should not be extended beyond 14 600mg without review see section 4. Clear clinical signs of infection at operation will require a normal course of intravenous or oral therapy post-operatively.
Elderly No dose injection is considered necessary. Renal impairment Dose adjustments are augmentin on the maximum recommended level of amoxicillin.
Hepatic 600mg Dose with caution and monitor hepatic function at regular intervals see sections 4, augmentin injection 600mg. Method of administration Augmentin is for intravenous use, augmentin injection 600mg. Augmentin may be administered either by slow intravenous injection over a period of 3 to 4 min directly into a vein or via a drip tube or by infusion over 30 to 40 min.
Augmentin is not suitable for intramuscular administration. Children aged less than 3 months should be administered Augmentin by infusion only.
IV Medication Administration: Reconstituting an IV Medication [UPDATED]
Treatment with Augmentin may be initiated by the use of an intravenous preparation and completed keflex 600mg an 600mg oral presentation as considered appropriate for the injection patient. For instructions on reconstitution and dilution of the medicinal product before administration, see section 6.
Augmentin of a severe immediate hypersensitivity reaction e. Serious and occasionally fatal hypersensitivity reactions including anaphylactoid and severe cutaneous adverse reactions have been reported in patients on penicillin therapy, augmentin injection 600mg. These reactions are more likely to occur in individuals with a history of penicillin hypersensitivity and in atopic individuals.
Augmentin Intravenous
This presentation of Augmentin may not be suitable for use when there is a high risk that the presumptive pathogens have resistance to beta-lactam agents that is not mediated by beta-lactamases susceptible to inhibition by clavulanic acid.
Convulsions may occur in patients with impaired renal function or in those receiving high doses see section 4. Concomitant use of allopurinol during treatment with amoxicillin can increase the likelihood of allergic skin reactions. Prolonged use may occasionally result in overgrowth of non-susceptible organisms. The occurrence at the treatment initiation of a feverish generalised erythema associated with pustula may be a symptom of acute generalised exanthemous pustulosis 600mg see section 4.
This reaction buy cetirizine pseudoephedrine Augmentin discontinuation and contraindicates any subsequent administration of amoxicillin. Hepatic events have been reported predominantly in males and elderly patients and may be comprar misoprostol 200mg with prolonged treatment, augmentin injection 600mg.
These events have been very rarely reported in children. In all populations, signs and symptoms usually occur during or shortly injection treatment but in some cases may not become apparent until several weeks after treatment has ceased. These are usually reversible. Hepatic events may be severe, and in extremely rare circumstances, deaths have been reported.
These have almost always occurred in patients with 600mg underlying disease or taking concomitant medications known to have the potential for hepatic effects see section 4. Antibiotic-associated colitis has been reported with nearly all antibacterial agents including augmentin and may range in fischer skischuh soma vacuum 110 from mild to life threatening see injection 4.
Therefore, it is important to consider this diagnosis in patients who present with diarrhoea during or subsequent to the administration of any antibiotics. Anti-peristaltic medicinal products are contraindicated in this situation. Periodic assessment of organ system functions, including renal, hepatic and haematopoietic function is order ativan online c.o.d during prolonged augmentin. Appropriate monitoring should be undertaken when anticoagulants are prescribed concomitantly.
Adjustments in the dose of oral anticoagulants may be necessary to maintain the desired level of anticoagulation see injections 4. In patients with renal impairment, the dose should be adjusted according to the degree of impairment see section 4. In patients with reduced urine output crystalluria has been observed very rarely, predominantly with parenteral therapy.
During the administration of augmentin doses of amoxicillin it is advisable to maintain adequate fluid intake and urinary output in order to reduce the possibility of amoxicillin crystalluria. In patients with bladder catheters, a regular check of patency should be maintained see section 4. During treatment with amoxicillin, enzymatic glucose oxidase methods should be used whenever testing for the presence of glucose in urine because false positive results may occur with non-enzymatic methods.
The presence of clavulanic acid in Augmentin may cause a non-specific binding of IgG and albumin by red cell membranes leading to a false positive Coombs test. To be taken into consideration by patients on a controlled sodium diet. To be taken into consideration by patients with reduced kidney function or patients on a controlled potassium diet. However, in the literature there are cases of increased international normalised ratio in patients maintained on acenocoumarol or warfarin and prescribed a course of amoxicillin.
If co-administration is necessary, the prothrombin time or international normalised ratio should be carefully monitored with the addition or withdrawal of amoxicillin. Moreover, adjustments in the dose of oral anticoagulants may be necessary see sections 4. Methotrexate Penicillins may reduce the excretion of methotrexate causing a potential increase in toxicity. Probenecid Concomitant use of probenecid is not recommended. Probenecid decreases the renal tubular secretion of amoxicillin.
Concomitant use of probenecid may result in increased and prolonged blood levels of amoxicillin but not of clavulanic acid. The change in pre-dose 600mg may not accurately represent changes in overall MPA exposure, augmentin injection 600mg. Therefore, a change in the dose of mycophenolate mofetil should not normally be necessary in the absence of clinical evidence of graft dysfunction.
However, close clinical monitoring should be performed during the combination and shortly after antibiotic treatment. Use should be avoided during pregnancy, unless considered essential by the physician, augmentin injection 600mg. Breastfeeding Both substances are excreted into breast milk nothing is known of the effects of clavulanic acid on the breast-fed infant.
Consequently, diarrhoea and fungus infection of the mucous membranes are possible in the fexofenadine online uk infant, so that breast-feeding might have to be discontinued.
The possibility of sensitisation should be taken into account. However, undesirable effects may occur e. The following terminologies have been used in order to classify the occurrence of undesirable effects.