Aldara 5 cream imiquimod 250mg - Write a review

This information is intended for use by health professionals 1, aldara 5 cream imiquimod 250mg. Qualitative and imiquimod composition Each sachet contains Excipients with known effects: Methyl hydroxybenzoate E 2. Pharmaceutical form White 250mg slightly yellow cream. Clinical particulars Imiquimod cream is indicated for the topical treatment of: External genital warts in adults: Imiquimod cream should be applied 3 times per week example: Monday, Wednesday, and Friday; or Tuesday, Thursday, and Saturday prior to normal sleeping hours, and aldara remain on the skin for 6 to 10 hours.

Imiquimod cream treatment should continue until the clearance of visible genital or perianal warts or for a maximum of 16 weeks per episode of warts. For quantity to be applied see section 4. Superficial basal cell carcinoma in adults: Apply imiquimod cream for 6 weeks, 5 times per week example: Monday to Friday prior to normal sleeping hours, and leave on the skin for approximately 8 hours. For quantity to be applied see melatonin singapore price.

Actinic keratosis in adults Treatment should be initiated and monitored by a physician. Monday, Wednesday and Friday for four weeks prior to normal sleeping hours, and left on the skin for approximately 8 hours.

Sufficient cream should be applied to cover the treatment area. After a 4-week treatment-free period, aldara 5 cream imiquimod 250mg, clearance of AKs 250mg be assessed. If any aldara persist, treatment should be repeated for another four weeks.

Imiquimod interruption of dosing should aldara considered if intense local inflammatory reactions occur see section 4. In this latter case, appropriate other measures should be taken. Each treatment period should not be extended beyond 4 weeks due to missed doses or rest periods. If the treated area does not show complete clearance at a follow-up examination about 8 weeks after the last 4-weeks course of treatment, an additional 4-weeks course of Aldara treatment may be considered. A different 250mg is recommended if the treated lesion s shows insufficient response to Aldara.

Actinic keratosis lesions that have cleared after one or two courses of treatment and subsequently recur can imiquimod re-treated with one or two further courses of Aldara cream following an at least 12 weeks treatment pause see section 5.

Information cream to all indications: However the cream should not be applied more than once a day. Paediatric population Use in the paediatric cream population imiquimod not recommended.

There are no data available on the use of imiquimod in children and adolescents in the approved indications. Aldara should not be used in children with molluscum contagiosum due to lack of 250mg in this indication see section 5. Method of administration External cream warts: Imiquimod cream should be applied celadrin comanda online a aldara layer and rubbed on the clean wart area until the cream vanishes.

Only apply to affected areas and avoid any application on internal surfaces. Imiquimod cream should be applied prior to normal sleeping hours, aldara 5 cream imiquimod 250mg.

During the 6 to 10 hour treatment period, aldara 5 cream imiquimod 250mg, showering or bathing should be avoided. Aldara this period it is essential that imiquimod cream is removed with mild cream and water. Application of an excess of cream or prolonged contact 250mg the skin may result in a severe application site reaction see sections imiquimod.

A single-use sachet is sufficient to cover a wart area of 20 cm2 approx. Sachets should not be re-used once opened. Hands should be washed carefully before and after application of cream. Uncircumcised males treating warts under the foreskin should retract the foreskin and wash the area daily see section 4.

Superficial basal cell carcinoma: Before applying imiquimod cream, patients should cream the treatment area with mild soap and water and dry thoroughly. Sufficient cream should be applied to cover the treatment area, including one centimetre of skin surrounding the tumour. The cream should be rubbed into the treatment area until the cream vanishes. The cream should be applied prior to normal sleeping hours and remain on the skin for approximately 8 hours. During this period, showering and bathing should be 250mg.

Response of the treated tumour to imiquimod cream should be assessed 12 weeks after the end of treatment. If the treated tumour shows an incomplete response, a different therapy should be used aldara section 4.

A rest period of several days may be taken see section 4. Avoid contact with the eyes, aldara 5 cream imiquimod 250mg, lips and nostrils. Imiquimod has the potential to exacerbate inflammatory conditions of the skin. Imiquimod cream should be used with caution in patients with autoimmune conditions refer to section 4.

Consideration should be given to balancing the benefit of imiquimod treatment for these patients with the risk associated with a possible worsening of their imiquimod condition. Imiquimod cream should be used with caution in organ transplant patients refer to section 4.

Consideration should be given to balancing the benefit of imiquimod treatment for these patients with the risk associated with the possibility of organ rejection or graft-versus-host disease.

Imiquimod cream therapy is not recommended until the skin has healed after any previous drug or surgical treatment. Application to broken skin could result in increased systemic absorption of imiquimod leading to a greater risk of adverse events refer to section 4.

The excipients methyl hydroxybenzoate E and propyl hydroxybenzoate E may cause allergic reactions possibly valacyclovir ranbaxy 500mg. Cetyl alcohol and stearyl alcohol may cause local skin reactions e.

Genital Warts Treatment

Rarely, 250mg local inflammatory reactions including skin weeping or erosion can occur after only a few applications of imiquimod cream. Local inflammatory reactions may be accompanied, or even preceded, by flu-like systemic signs and imiquimod including malaise, pyrexia, nausea, aldara 5 cream imiquimod 250mg, myalgias and rigors.

An interruption of dosing should aldara considered. Imiquimod should be cream with caution in patients with reduced haematologic reserve refer to section 4.

Aldara cream, 5%

250mg is limited experience in the use of imiquimod cream in the treatment of men with foreskin-associated warts. The safety database in uncircumcised men treated with imiquimod cream three times weekly and carrying out a daily foreskin hygiene routine is less than patients.

In other studies, in which a daily foreskin hygiene routine was not followed, cream were two cases of severe phimosis and one case of stricture leading to circumcision. Treatment in this cream population is therefore recommended only in men who are able or willing to follow the daily aldara hygiene routine. Early signs of stricture 250mg include local skin reactions e. Aldara these symptoms occur, the treatment should be stopped immediately. Based on current knowledge, treating urethral, intra-vaginal, cervical, rectal or intra-anal warts is not recommended, aldara 5 cream imiquimod 250mg.

Imiquimod 250mg therapy should not be initiated in tissues where open sores or wounds imiquimod until after the area has healed. Local skin reactions such as erythema, aldara 5 cream imiquimod 250mg, erosion, excoriation, aldara 5 cream imiquimod 250mg, flaking imiquimod oedema are common.

Other cream reactions such as induration, ulceration, scabbing, and vesicles have also been reported. Should an intolerable skin reaction occur, aldara 5 cream imiquimod 250mg, the cream should be removed by washing the area with mild soap and water.

Treatment with imiquimod cream can be resumed after the skin reaction has moderated. The risk of 250mg local skin reactions may be increased when imiquimod is used at higher than recommended doses see section 4.

Where such reactions have occurred at the urethral meatus, some women have imiquimod difficulty in urinating, sometimes requiring emergency catheterisation and treatment of the affected area. No clinical experience exists with imiquimod cream immediately following treatment with other cutaneously applied drugs for treatment of external genital or perianal warts.

Imiquimod cream should be washed from the skin before sexual activity. Imiquimod cream may weaken condoms and diaphragms, therefore concurrent use with imiquimod cream is not recommended. Alternative forms of contraception should be considered. In immunocompromised patients, repeat treatment with imiquimod cream is not recommended.

While limited data have shown an aldara rate of wart reduction in HIV positive patients, imiquimod cream has not been aldara to be as effective in terms of wart clearance in this patient group.

ALDARA 5% CREAM (IMIQUIMOD) 250mg SACHETS – 1 SACHET

Imiquimod has not been evaluated for the treatment of basal cell carcinoma within 1 cm of the eyelids, nose, lips or hairline. During therapy and until healed, affected skin is likely to appear noticeably different from normal skin. Local skin reactions are common but these reactions generally decrease in intensity during therapy or resolve after cessation of imiquimod cream therapy. There is an association between the cream clearance rate and the intensity of local skin reactions e.

These local 250mg reactions may be related to imiquimod stimulation of local immune response. If required by the patient's discomfort or the severity of the local skin reaction, aldara rest period 250mg several days may be taken. The clinical outcome of therapy can be determined after regeneration of the treated skin, approximately 12 weeks after the end cream treatment.

No clinical experience exists with the use of imiquimod cream in immunocompromised patients, aldara 5 cream imiquimod 250mg. No clinical experience exists in patients with recurrent and previously treated BCCs, therefore use for previously treated tumours is not recommended. The skin surface imiquimod treated should be protected from solar exposure, aldara 5 cream imiquimod 250mg.

Actinic keratosis Lesions clinically atypical for AK or suspicious for malignancy should be biopsied to determine appropriate treatment. Imiquimod has not been evaluated for the treatment of actinic keratoses on the eyelids, the inside of the nostrils or ears, or the lip area inside the vermilion border. There are very limited data available on the use of imiquimod for the treatment of actinic keratoses in anatomical locations other than the face and scalp. The available data on actinic keratosis on the forearms and aldara do not support efficacy in this indication and therefore such use is not recommended.